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Article

A common P2 promoter polymorphism of the hepatocyte nuclear factor-4alpha gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes.

Endocrine journal - 1 Dec 2008

Tokunaga Ayumi, Horikawa Yukio, Fukuda-Akita Etsuko, Okita Kohei, Iwahashi Hiromi, Shimomura Iichiro, Takeda Jun, Yamagata Kazuya

Abstract excerpt

AIMS: Heterozygous mutations of the hepatocyte nuclear factor (HNF)-4alpha gene cause a particular form of maturity-onset diabetes of the young (MODY1). Recent genetic studies have shown that single nucleotide polymorphisms (SNPs) of the beta-cell type P2 promoter of the HNF-4alpha gene are assoc...

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Source

Identifiers

PMID: 18654034
DOI: 10.1507/endocrj.k08e-083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18654034-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A common P2 promoter polymorphism of the hepatocyte nuclear factor-4alpha gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes.PMID 18654034Read ↗

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