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Article

Extracellular superoxide production by Enterococcus faecalis promotes chromosomal instability in mammalian cells.

Gastroenterology - 1 Feb 2007

Wang Xingmin, Huycke Mark M

Abstract excerpt

BACKGROUND & AIMS: We investigated whether Enterococcus faecalis, a Gram-positive intestinal commensal that produces extracellular superoxide, could promote chromosomal instability (CIN) in mammalian cells. METHODS: We measured the ability of E faecalis to promote CIN using hybrid hamster cells (A(L)N) containing human chromosome 11. RESULTS: E faecalis promoted CIN in A(L)N cells with average mutant fractions...

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Identifiers

PMID: 17258726
DOI: 10.1053/j.gastro.2006.11.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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