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Article

Quantitative analysis of Howell-Jolly bodies in children with sickle cell disease.

Experimental hematology - 1 Feb 2007

Harrod Virginia L, Howard Thad A, Zimmerman Sherri A, Dertinger Stephen D, Ware Russell E

Abstract excerpt

OBJECTIVES: Although functional asplenia in sickle cell disease (SCD) begins early in life and has important clinical consequences, quantitative measurement of splenic function is not readily available. A novel high-throughput flow cytometric method for quantitating Howell-Jolly bodies (HJB) has been developed which isolates HJB-containing CD71(+) and CD71(-) erythrocytes. Analysis of these cell populations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17258066
DOI: 10.1016/j.exphem.2006.09.013

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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