Article
New insights into the function and regulation of vitamin D target proteins.
The Journal of steroid biochemistry and molecular biology - 1 Mar 2007
Christakos Sylvia, Dhawan Puneet, Peng Xiaorong, Obukhov Alexander G, Nowycky Martha C, Benn Bryan S, Zhong Yan, Liu Yan, Shen Qi
Abstract excerpt
Calbindin-D(28k) has been reported to be a facilitator of calcium diffusion and to protect against apoptotic cell death. Most recently, we found that the presence of calbindin-D(28k) results in reduced calcium influx through voltage-dependent L-type Ca(2+) channels and enhanced sensitivity of the channels to calcium dependent inactivation. Co-immunoprecipitation and GST pull down assays indicate that...
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