Article
Mapping of a self-interaction domain of the cytomegalovirus protein kinase pUL97.
The Journal of general virology - 1 Feb 2007
Schregel Vera, Auerochs Sabrina, Jochmann Ramona, Maurer Katja, Stamminger Thomas, Marschall Manfred
Abstract excerpt
The human cytomegalovirus-encoded protein kinase pUL97 is a determinant of efficient virus replication and fulfils several regulatory functions. In particular, pUL97 interacts with and phosphorylates viral and cellular proteins. Substrate phosphorylation has regulatory consequences on viral replicative stages such as DNA synthesis, transcription and nuclear capsid egress. pUL97, in accordance with related...
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