Article
The protein kinase pUL97 of human cytomegalovirus interacts with and phosphorylates the DNA polymerase processivity factor pUL44.
Virology - 20 Jun 2003
Marschall Manfred, Freitag Martina, Suchy Patricia, Romaker Daniel, Kupfer Regina, Hanke Miriam, Stamminger Thomas
Abstract excerpt
The protein kinase pUL97 of human cytomegalovirus plays important but incompletely defined roles in viral replication. Concerning the early phase of infection, it is postulated that pUL97 possesses regulatory functions in gene expression and/or DNA synthesis. Here we report that pUL97 interacts with an essential component of the replication complex, the DNA polymerase processivity factor pUL44. Interaction was...
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