Article
Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.
Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2007
Petrou Petros, Pavlakis Evangelos, Dalezios Yannis, Chalepakis Georges
Abstract excerpt
The Fraser syndrome protein Fras1 and the structurally related proteins Frem1, Frem2 and Frem3 comprise a novel family of extracellular matrix proteins implicated in the structural adhesion of the embryonic epidermis to the underlying mesenchyme. Fras1, Frem1 and Frem2 have been shown to be simultaneously and interdependently stabilized in the basement membrane by forming a ternary complex located underneath the...
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