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Article

Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis.

Cancer - 15 Feb 2007

Attard Thomas M, Giglio Pierre, Koppula Sireesha, Snyder Carrie, Lynch Henry T

Abstract excerpt

BACKGROUND: Most individuals with Familial Adenomatous Polyposis (FAP) harbor mutations in the APC gene on chromosome 5q21. They are at an increased risk of brain tumors, including cerebellar medulloblastoma, when compared with the general population (Brain Tumor Polyposis-BTP Type 2). Genotype-phenotype correlations between APC gene mutations and central nervous system (CNS) tumors have, thus far not been...

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Identifiers

PMID: 17238184
DOI: 10.1002/cncr.22475

Genes

APC
FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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