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Article

Inhibitory effects of neurotransmitters and steroids on human CYP2A6.

Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2007

Higashi Eriko, Nakajima Miki, Katoh Miki, Tokudome Shogo, Yokoi Tsuyoshi

Abstract excerpt

Human CYP2A6 catalyzes the metabolism of nicotine, cotinine, and coumarin as well as some pharmaceutical drugs. CYP2A6 is highly expressed in liver and, also, in brain and steroid-related tissues. In this study, we investigated the inhibitory effects of neurotransmitters and steroid hormones on C...

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Identifiers

PMID: 17237153
DOI: 10.1124/dmd.106.014084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17237153-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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