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Article

Novel Function of the Ciliogenic Transcription Factor RFX3 in Development of the Endocrine Pancreas

29 Mar 2007

Abstract excerpt

The transcription factor regulatory factor X (RFX)-3 regulates the expression of genes required for the growth and function of cilia. We show here that mouse RFX3 is expressed in developing and mature pancreatic endocrine cells during embryogenesis and in adults. RFX3 expression already is evident in early Ngn3-positive progenitors and is maintained in all major pancreatic endocrine cell lineages throughout their...

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PMID: 17229940
DOI: 10.2337/db06-1187

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Related research

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Novel Function of the Ciliogenic Transcription Factor RFX3 in Development of the Endocrine PancreasPMID 17229940Read ↗

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