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Article

Mechanism of fusion triggering by human parainfluenza virus type III: communication between viral glycoproteins during entry.

The Journal of biological chemistry - 2 Jan 2012

Porotto Matteo, Palmer Samantha G, Palermo Laura M, Moscona Anne

Abstract excerpt

Parainfluenza viruses enter host cells by fusing the viral and target cell membranes via concerted action of their two envelope glycoproteins: the hemagglutinin-neuraminidase (HN) and the fusion protein (F). Receptor-bound HN triggers F to undergo conformational changes that render it fusion-competent. To address the role of receptor engagement and to elucidate how HN and F interact during the fusion process, we...

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Share to Hemagglutinins, Viral
Share to Molecular Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuraminidase

Share to Protein Multimerization

Share to Protein Structure, Quaternary

Share to Spectrometry, Fluorescence

Share to Viral Fusion Proteins

Share to Virus Internalization

Source

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Identifiers

PMID: 22110138
DOI: 10.1074/jbc.M111.298059
PMCID: PMC3249132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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