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Article

The location of a closed channel gate in the GABAA receptor channel.

The Journal of general physiology - 1 Feb 2007

Bali Moez, Akabas Myles H

Abstract excerpt

Considerable controversy surrounds the location of the closed channel gate in members of the Cys-loop receptor family of neurotransmitter-gated ion channels that includes the GABAA, glycine, acetylcholine, and 5-HT3 receptors. Cysteine-accessibility studies concluded that the gate is near the cytoplasmic end of the channel in acetylcholine and GABAA receptors but in the middle of the 5-HT3A receptor channel. Zn2+...

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Identifiers

PMID: 17227918
DOI: 10.1085/jgp.200609639
PMCID: PMC2154354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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