Article
The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages.
1 Jan 2007
Abstract excerpt
With the prospect of another pandemic Influenza fresh in our consciousness, the pathogenic nature of the Influenza A virus and its ability to induce high rates of mortality are ever more pertinent. Recently a novel protein encoded by an alternate reading frame in the PB1 Gene segment of Influenza A virus has been discovered and in turn shown to enhance viral virulence in a mouse model 1. This protein has been...
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