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Article

Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82.

Journal of virology - 1 Dec 2011

Alymova Irina V, Green Amanda M, van de Velde Nicholas, McAuley Julie L, Boyd Kelli L, Ghoneim Hazem E, McCullers Jonathan A

Abstract excerpt

The influenza A virus protein PB1-F2 has been linked to the pathogenesis of both primary viral and secondary bacterial infections. H3N2 viruses have historically expressed full-length PB1-F2 proteins with either proinflammatory (e.g., from influenza A/Hong Kong/1/1968 virus) or noninflammatory (e.g., from influenza A/Wuhan/359/1995 virus) properties. Using synthetic peptides derived from the active C-terminal...

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Identifiers

PMID: 21937639
DOI: 10.1128/JVI.05872-11
PMCID: PMC3209399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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