Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c Mice

19 Mar 2015

Abstract excerpt

UNLABELLED: Influenza A viruses (IAVs) express the PB1-F2 protein from an alternate reading frame within the PB1 gene segment. The roles of PB1-F2 are not well understood but appear to involve modulation of host cell responses. As shown in previous studies, we find that PB1-F2 proteins of mammalian IAVs frequently have premature stop codons that are expected to cause truncations of the protein, whereas avian IAVs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to Respiratory viral infections research
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25787281
DOI: 10.1128/jvi.03137-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c MicePMID 25787281Read ↗

Evolution and Virulence of Influenza A Virus Protein PB1-F2Semantic proximity Read ↗

Transcriptomic Analysis of Host Immune and Cell Death Responses Associated with the Influenza A Virus PB1-F2 ProteinSemantic proximity Read ↗

PB1-F2 attenuates virulence of highly pathogenic avian H5N1 influenza virus in chickens.Semantic proximity Read ↗

Kinetic Characterization of PB1-F2-Mediated Immunopathology during Highly Pathogenic Avian H5N1 Influenza Virus InfectionSemantic proximity Read ↗

Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian SpeciesSemantic proximity Read ↗

Is PB1-F2 a virulence factor for avian influenza virus in poultry?Semantic proximity Read ↗

Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene.Semantic proximity Read ↗

Influenza A virus PB1-F2 protein: An ambivalent innate immune modulator and virulence factorSemantic proximity Read ↗

Influenza A virus PB1-F2 protein prolongs viral shedding in chickens lengthening the transmission windowSemantic proximity Read ↗

Study of the host specificity of PB1-F2-associated virulenceSemantic proximity Read ↗

PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus.Semantic proximity Read ↗

Adaptive mutations in PB2 gene contribute to the high virulence of a natural reassortant H5N2 avian influenza virus in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.