Article
Confocal microscopy of genome exposure in normal, cancer, and reverse-transformed cells.
Somatic cell and molecular genetics - 1 Sept 1991
Puck T T, Bartholdi M, Krystosek A, Johnson R, Haag M
Abstract excerpt
Genome exposure studies were carried out on malignant CHO-K1 and C6 rat glioma cells and their respective, phenotypically normal counterparts (reverse-transformed CHO-K1, and both reverse-transformed C6 glioma and normal rat fibroblasts). Cells were subjected to the nick-translation technique pre...
Topics
- 1-Methyl-3-isobutylxanthine
- 8-Bromo Cyclic Adenosine Monophosphate
- Animals
- Bucladesine
- CHO Cells
- Cell Nucleolus
- Cell Nucleus
- Cell Transformation, Neoplastic
- Cricetinae
- DNA
- DNA, Neoplasm
- Deoxyribonuclease I
- Fibroblasts
- Genome
- Microscopy, Fluorescence
- Phenotype
- Tumor Cells, Cultured