Article
Confocal microscopy of genome exposure in normal, cancer, and reverse-transformed cells.
Somatic cell and molecular genetics - 1 Sept 1991
Puck T T, Bartholdi M, Krystosek A, Johnson R, Haag M
Abstract excerpt
Genome exposure studies were carried out on malignant CHO-K1 and C6 rat glioma cells and their respective, phenotypically normal counterparts (reverse-transformed CHO-K1, and both reverse-transformed C6 glioma and normal rat fibroblasts). Cells were subjected to the nick-translation technique previously developed to make visible the exposed (i.e., DNase I-sensitive) nuclear DNA, and examined by both...
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