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Article

Cellular Response to DNA Damage

1 Mar 2006

Abstract excerpt

Eukaryotic cells, from yeast to man, possess evolutionarily conserved mechanisms to accurately and efficiently repair the overwhelming majority of DNA damage, thereby ensuring genomic integrity. Important repair pathways include base excision repair, nucleotide excision repair, mismatch repair, non-homologous end-joining, and homologous recombination. Defects in DNA repair processes generally result in...

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PMID: 16533929
DOI: 10.1196/annals.1363.012

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