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Article

The dimerization of an alpha/beta-knotted protein is essential for structure and function.

Structure (London, England : 1993) - 1 Jan 2007

Mallam Anna L, Jackson Sophie E

Abstract excerpt

alpha/beta-Knotted proteins are an extraordinary example of biological self-assembly; they contain a deep topological trefoil knot formed by the backbone polypeptide chain. Evidence suggests that all are dimeric and function as methyltransferases, and the deep knot forms part of the active site. We investigated the significance of the dimeric structure of the alpha/beta-knot protein, YibK, from Haemophilus...

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Identifiers

PMID: 17223537
DOI: 10.1016/j.str.2006.11.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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