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Article

Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter.

The EMBO journal - 24 Mar 2004

Yeo Hye-Jeong, Cotter Shane E, Laarmann Sven, Juehne Twyla, St Geme Joseph W, Waksman Gabriel

Abstract excerpt

Haemophilus influenzae is an important human pathogen that initiates infection by colonizing the upper respiratory tract. The H. influenzae Hia autotransporter is an adhesive protein that promotes adherence to respiratory epithelial cells. Hia adhesive activity resides in two homologous binding domains, called HiaBD1 and HiaBD2. These domains interact with the same host cell receptor, but bind with different...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15029242
DOI: 10.1038/sj.emboj.7600142
PMCID: PMC381414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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