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Article

Energy landscape of knotted protein folding.

Proceedings of the National Academy of Sciences of the United States of America - 30 Oct 2012

Sułkowska Joanna I, Noel Jeffrey K, Onuchic Jose N

Abstract excerpt

Recent experiments have conclusively shown that proteins are able to fold from an unknotted, denatured polypeptide to the knotted, native state without the aid of chaperones. These experiments are consistent with a growing body of theoretical work showing that a funneled, minimally frustrated ene...

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Identifiers

PMID: 22891304
DOI: 10.1073/pnas.1201804109
PMCID: PMC3497829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22891304-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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