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Article

Genetic and epigenetic alteration profiles for multiple genes in salivary gland carcinomas.

Oral oncology - 1 Feb 2005

Kishi Munehiro, Nakamura Mitsutoshi, Nishimine Masayoshi, Ikuta Miwa, Kirita Tadaaki, Konishi Noboru

Abstract excerpt

As combinations of genetic and/or epigenetic alterations occurring during salivary gland carcinogenesis are largely unknown, we here analyzed 36 salivary gland carcinomas (SGCs) for changes in INK4a/ARF, RB1, p21, p27, PTEN, p53, MDM2 and O6-MGMT genes using methylation specific PCR (MSP), loss of heterozygosity (LOH) assays and mutational analysis with immunohistochemistry (IHC), as well as histone H3 and H4...

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Identifiers

PMID: 15695118
DOI: 10.1016/j.oraloncology.2004.08.004

Genes

MGMT
PTEN
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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