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Article

Peptidoglycan deacetylation in Helicobacter pylori contributes to bacterial survival by mitigating host immune responses.

Infection and immunity - 1 Nov 2010

Wang Ge, Maier Susan E, Lo Leja F, Maier George, Dosi Shruti, Maier Robert J

Abstract excerpt

An oxidative stress-induced enzyme, peptidoglycan deacetylase (PgdA), in the human gastric pathogen Helicobacter pylori was previously identified and characterized. In this study, we constructed H. pylori pgdA mutants in two mouse-adapted strains, X47 and B128, to investigate the role of PgdA in vivo (to determine the mutants' abilities to colonize mice and to induce an immune response). H. pylori pgdA mutant...

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Source

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Identifiers

PMID: 20805339
DOI: 10.1128/IAI.00307-10
PMCID: PMC2976313

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MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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