Article
ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations.
Biochemical and biophysical research communications - 23 Feb 2007
la Cour Jonas M, Mollerup Jens, Berchtold Martin Werner
Abstract excerpt
A variety of stimuli can trigger intracellular calcium oscillations. Relatively little is known about the molecular mechanisms decoding these events. We show that ALG-2, a Ca2+-binding protein originally isolated as a protein associated with apoptosis, is directly linked to Ca2+ signalling. We discovered that the subcellular distribution of a tagged version of ALG-2 could be directed by physiological external...
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