Article
Crystal Structure and Function of the Zinc Uptake Regulator FurB from Mycobacterium tuberculosis
10 Jan 2007
Abstract excerpt
Members of the ferric/zinc uptake regulator (Fur/Zur) family are the central metal-dependent regulator proteins in many Gram-negative and -positive bacteria. They are responsible for the control of a wide variety of basic physiological processes and the expression of important virulence factors in human pathogens. Therefore, Fur has gathered significant interest as a potential target for novel antibiotics. Here...
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