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Article

Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C.

The Journal of biological chemistry - 23 Mar 2007

Shao Chenghua, Shi Xiaomeng, Wehbi Hania, Zambonelli Carlo, Head James F, Seaton Barbara A, Roberts Mary F

Abstract excerpt

The crystal structure of the W47A/W242A mutant of phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus thuringiensis has been solved to 1.8A resolution. The W47A/W242A mutant is an interfacially challenged enzyme, and it has been proposed that one or both tryptophan side chains serve as membrane interfacial anchors (Feng, J., Wehbi, H., and Roberts, M. F. (2002) J. Biol. Chem. 277, 19867-19875)....

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Source

Identifiers

PMID: 17213187
DOI: 10.1074/jbc.M610918200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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