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Article

Derivative (14)t(11;14)(q13;q32)t(11;14)(p11.2;p11.2): a novel unbalanced variant of the t(11;14)(q13;q32) translocation in mantle cell lymphoma.

Cancer genetics and cytogenetics - 15 Jan 2007

Sathanoori Malini, Shekhter-Levin Sofia, Marks Stanley M, Swerdlow Steven H

Abstract excerpt

We report the case of a 62-year-old man who presented with splenomegaly, leukocytosis, anemia, and thrombocytopenia. Examination of the peripheral blood, bone marrow, and spleen revealed involvement by mantle cell lymphoma, with some blastoid features and an atypical phenotype. Spleen and bone marrow classical chromosome analysis followed by fluorescence in situ hybridization revealed a novel and unusual...

Topics

Allelic Imbalance
Bone Marrow Neoplasms
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 14
Cyclin D1
Genetic Variation
Humans
Immunoglobulin Heavy Chains
Lymphoma, Mantle-Cell
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Oncogene Proteins, Fusion

Splenic Neoplasms

Translocation, Genetic

Source

Identifiers

PMID: 17213026
DOI: 10.1016/j.cancergencyto.2006.09.005

Genes

CCND1
IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Derivative (14)t(11;14)(q13;q32)t(11;14)(p11.2;p11.2): a novel unbalanced variant of the t(11;14)(q13;q32) translocation in mantle cell lymphoma.PMID 17213026Read ↗

Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas.Semantic proximity Read ↗

Variant t(2;11)(p11;q13) associated with the IgK-CCND1 rearrangement is a recurrent translocation in leukemic small-cell B-non-Hodgkin lymphoma.Semantic proximity Read ↗

Mantle cell lymphoma with a novel t(11;12)(q13;p11.2): a proposed alternative mechanism of CCND1 up-regulation.Semantic proximity Read ↗

t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)Semantic proximity Read ↗

Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosisSemantic proximity Read ↗

Variant t(2;11)(p11.2;q13) without IGK involvement in a case of mantle cell lymphoma.Semantic proximity Read ↗

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.Semantic proximity Read ↗

The (11;14)(q13;q32) Translocation in Multiple MyelomaSemantic proximity Read ↗

Clinical, Morphologic, Phenotypic, and Genetic Evidence of Cyclin D1-positive Diffuse Large B-cell Lymphomas With CYCLIN D1 Gene RearrangementsSemantic proximity Read ↗

[Clinical and molecular cytogenetic studies of a case of B-lineage acute lymphoblastic leukemia with t(14;14)(q11;q32)].Semantic proximity Read ↗

Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphomaSemantic proximity Read ↗

BCL-1 rearrangements and p53 mutations in atypical chronic lymphocytic leukemia with t(11;14)(q13;q32).Semantic proximity Read ↗

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