Article
Extracellular domain splice variants of a transforming protein tyrosine phosphatase alpha mutant differentially activate Src-kinase dependent focus formation.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2007
Kapp Katja, Siemens Jan, Weyrich Peter, Schulz Jörg B, Häring Hans-Ulrich, Lammers Reiner
Abstract excerpt
The extracellular domains of receptor-type protein-tyrosine phosphatases (PTPs) contain a diverse range of protein modules like fibronectin- or immunoglobulin-like structures. These are frequently expressed in a tissue- and development specific manner as splice variants. The extracellular domain of PTPalpha is rather short and heavily glycosylated. Two splice variants are known, which it differs by an exon...
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