Article
Expression pattern and subcellular localization of five splice isoforms of human PXK.
International journal of molecular medicine - 1 Oct 2005
Zou Xianqiong, Qiu Guanzhou, Chen Chunjing, Wu Maoqing, Hu Yuehua, Zheng Huarui, Li Xin, Gu Shaohua, Ji Chaoneng, Mao Yumin
Abstract excerpt
Phox homology (PX) domains specifically bind to phosphoinositides, and this interaction is crucial for their cellular function. A full-length cDNA of human PX domain containing serine/threonine kinase gene (PXK) that we termed PXK_v1 had previously been cloned. PXK_v1 consists of a S_TKc domain (serine/threonine kinases, catalytic domain), but lacks several residues that are indispensable for intrinsic catalytic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
