Article
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.
Oncogene - 28 Apr 2005
Pera Ilaria Le, Iuliano Rodolfo, Florio Tullio, Susini Christiane, Trapasso Francesco, Santoro Massimo, Chiariotti Lorenzo, Schettini Gennaro, Viglietto Giuseppe, Fusco Alfredo
Abstract excerpt
The expression of the receptor protein tyrosine phosphatase r-PTPeta is drastically reduced in rat and human malignant thyroid cells, whereas its restoration reverts the neoplastic phenotype of retrovirally transformed rat thyroid cells. Moreover, reduced levels and loss of heterozygosity of DEP-...
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