Article
Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.
The Biochemical journal - 15 Jun 2003
Leder Susanne, Czajkowska Hanna, Maenz Barbara, De Graaf Katrin, Barthel Andreas, Joost Hans-Georg, Becker Walter
Abstract excerpt
The dual specificity tyrosine phosphorylated and regulated kinase (DYRK) family of protein kinases is a group of evolutionarily conserved protein kinases that have been characterized as regulators of growth and development in mammals, Drosophila and lower eukaryotes. In the present study, we have characterized three splicing variants of DYRK1B (DYRK1B-p65, DYRK1B-p69 and DYRK1B-p75) with different expression...
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