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Article

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD.

PLoS medicine - 1 Jan 2006

Magnusson Kristinn P, Duan Shan, Sigurdsson Haraldur, Petursson Hjorvar, Yang Zhenglin, Zhao Yu, Bernstein Paul S, Ge Jian, Jonasson Fridbert, Stefansson Einar, Helgadottir Gudleif, Zabriskie Norman A, Jonsson Thorlakur, Björnsson Asgeir, Thorlacius Theodora, Jonsson Palmi V, Thorleifsson Gudmar, Kong Augustine, Stefansson Hreinn, Zhang Kang, Stefansson Kari, Gulcher Jeffrey R

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that lead to loss of central vision...

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Source

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Identifiers

PMID: 16300415
DOI: 10.1371/journal.pmed.0030005
PMCID: PMC1288033

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16300415-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD.PMID 16300415Read ↗

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