Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathway of biogenesis of apolipoprotein E-containing HDL <i>in vivo</i> with the participation of ABCA1 and LCAT

26 Mar 2007

Abstract excerpt

We have investigated the ability of apoE (apolipoprotein E) to participate in the biogenesis of HDL (high-density lipoprotein) particles in vivo using adenovirus-mediated gene transfer in apoA-I-/- (apolipoprotein A-I) or ABCA1-/- (ATP-binding cassette A1) mice. Infection of apoA-I-/- mice with 2x10(9) pfu (plaque-forming units) of an apoE4-expressing adenovirus increased both HDL and the triacylglycerol-rich...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17206937
DOI: 10.1042/bj20061048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathway of biogenesis of apolipoprotein E-containing HDL <i>in vivo</i> with the participation of ABCA1 and LCATPMID 17206937Read ↗

ABCA1 Promotes the de Novo Biogenesis of Apolipoprotein CIII-Containing HDL Particles in Vivo and Modulates the Severity of Apolipoprotein CIII-Induced HypertriglyceridemiaSemantic proximity Read ↗

Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.Semantic proximity Read ↗

Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL.Semantic proximity Read ↗

LCAT can rescue the abnormal phenotype produced by the natural ApoA-I mutations (Leu141Arg)Pisa and (Leu159Arg)FIN.Semantic proximity Read ↗

Both Hepatic and Extrahepatic ABCA1 Have Discrete and Essential Functions in the Maintenance of Plasma High-Density Lipoprotein Cholesterol Levels In VivoSemantic proximity Read ↗

In vivo studies of HDL assembly and metabolism using adenovirus-mediated transfer of ApoA-I mutants in ApoA-I-deficient mice.Semantic proximity Read ↗

HDL Dysfunction Caused by Mutations in apoA-I and Other Genes that are Critical for HDL Biogenesis and Remodeling.Semantic proximity Read ↗

Significance of the hydrophobic residues 225-230 of apoA-I for the biogenesis of HDL.Semantic proximity Read ↗

Role of the hydrophobic and charged residues in the 218-226 region of apoA-I in the biogenesis of HDL.Semantic proximity Read ↗

An overview of reverse cholesterol transport.Semantic proximity Read ↗

Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano.Semantic proximity Read ↗

Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.