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Article

[Detection of IgVH mutation status in patients with chronic lymphocytic leukemia by multiplex PCR].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2006

Zheng Wen-Juan, Chen Li-Juan, Wu Yu-Jie, Li Li, Xu Wei, Li Jian-Yong

Abstract excerpt

IgVH mutation status is one of the most important independent prognostic factor of chronic lymphocytic leukemia (CLL). In order to evaluate IgVH mutation status in patients with CLL, IgVH mutation was detected by multiplex PCR in 9 CLL patients and purified PCR amplification products were directly sequenced, IgH somatic hypermutation and mutation site were analysed by IMGT/V-QUEST. The results showed that 5...

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Identifiers

PMID: 17204172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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