Article
VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis.
BMC musculoskeletal disorders - 4 Jan 2007
Butt Christopher, Lim Sooyeol, Greenwood Celia, Rahman Proton
Abstract excerpt
BACKGROUND: Angiogenesis appears to be a first-order event in psoriatic arthritis (PsA). Among angiogenic factors, the cytokines vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and fibroblast growth factors 1 and 2 (FGF1 and FGF2) play a central role in the initiation of angiogenesis. Most of these cytokines have been shown to be upregulated in or associated with psoriasis, rheumatoid...
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