Article
Investigation on association between five common polymorphisms in vascular endothelial growth factor and prototypes of autoimmune diseases.
Immunobiology - 1 Jun 2015
Che Nan, Li Yongsheng, Liu Shanshan, Pan Wenyou, Liu Yan
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF) is a crucial regulator in angiogenesis. Previous research has indicated that modified VEGF-VEGFR signaling pathway has an impact on the development of inflammatory diseases. It has been proved that single nucleotide polymorphisms (SNPs) for critical genes might be associated with the susceptibility of autoimmune diseases. In this study, we targeted five common...
Topics
- Alleles
- Autoimmune Diseases
- Case-Control Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Odds Ratio
- Polymorphism, Single Nucleotide
- Publication Bias
- Vascular Endothelial Growth Factors