Article
Overexpression of aldo-keto reductase 1C2 as a high-risk factor in bladder cancer.
Oncology reports - 1 Feb 2007
Tai Hui-Lung, Lin Torng-Sen, Huang Hsuan-Hua, Lin Tze-Yi, Chou Ming-Chih, Chiou Shiow-Her, Chow Kuan-Chih
Abstract excerpt
Intravesical adjuvant chemotherapy and neoadjuvant chemotherapy has been respectively administered for superficial transitional cell carcinoma (TCC) of urinary bladder and advanced TCC for years. However, the therapeutic efficacy is limited. Recently, overexpression of aldo-keto reductase (AKR) in lung, esophageal, uterine cervical and ovarian cancers was shown to be closely associated with disease progression...
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