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Article

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.

Developmental cell - 1 Jan 2007

Tadros Wael, Goldman Aaron L, Babak Tomas, Menzies Fiona, Vardy Leah, Orr-Weaver Terry, Hughes Timothy R, Westwood J Timothy, Smibert Craig A, Lipshitz Howard D

Abstract excerpt

In animals, egg activation triggers a cascade of posttranscriptional events that act on maternally synthesized RNAs. We show that, in Drosophila, the PAN GU (PNG) kinase sits near the top of this cascade, triggering translation of SMAUG (SMG), a multifunctional posttranscriptional regulator conse...

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Identifiers

PMID: 17199047
DOI: 10.1016/j.devcel.2006.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17199047-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.PMID 17199047Read ↗

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