Article
Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression.
The EMBO journal - 14 Jan 2004
Nelson Meryl R, Leidal Andrew M, Smibert Craig A
Abstract excerpt
Translational regulation plays an essential role in development and often involves factors that interact with sequences in the 3' untranslated region (UTR) of specific mRNAs. For example, Nanos protein at the posterior of the Drosophila embryo directs posterior development, and this localization requires selective translation of posteriorly localized nanos mRNA. Spatial regulation of nanos translation requires...
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