Article
Genetic polymorphism of the angiotensin converting enzyme and L-dopa-induced adverse effects in Parkinson's disease.
Journal of the neurological sciences - 31 Jan 2007
Lin Juei-Jueng, Yueh Kuo-Chu, Lin Shinn-Zong, Harn Horng-Jyh, Liu Jung-Tung
Abstract excerpt
There was increasing evidence suggesting that angiotensin I-converting enzyme may play an important role in the pathogenesis of PD. Our former study has shown that angiotensin I-converting enzyme gene (ACE) may confer a susceptibility for the risk of Parkinson's disease (PD). Meanwhile, recent studies have emphasized that genetic factors may involve in the occurrence of the adverse effects of chronic L-dopa...
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