Article
The structure of linkage disequilibrium around a selective sweep.
Genetics - 1 Mar 2007
McVean Gil
Abstract excerpt
The fixation of advantageous mutations by natural selection has a profound impact on patterns of linked neutral variation. While it has long been appreciated that such selective sweeps influence the frequency spectrum of nearby polymorphism, it has only recently become clear that they also have dramatic effects on local linkage disequilibrium. By extending previous results on the relationship between genealogical...
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