Article
Linkage disequilibrium under genetic hitchhiking in finite populations.
Genetics - 1 May 2008
Pfaffelhuber P, Lehnert A, Stephan W
Abstract excerpt
The model of genetic hitchhiking predicts a reduction in sequence diversity at a neutral locus closely linked to a beneficial allele. In addition, it has been shown that the same process results in a specific pattern of correlations (linkage disequilibrium) between neutral polymorphisms along the chromosome at the time of fixation of the beneficial allele. During the hitchhiking event, linkage disequilibrium on...
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