Article
Estimating the strength of selective sweeps from deep population diversity data.
Genetics - 1 Jun 2012
Messer Philipp W, Neher Richard A
Abstract excerpt
Selective sweeps are typically associated with a local reduction of genetic diversity around the adaptive site. However, selective sweeps can also quickly carry neutral mutations to observable population frequencies if they arise early in a sweep and hitchhike with the adaptive allele. We show that the interplay between mutation and exponential amplification through hitchhiking results in a characteristic...
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