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Article

Lipoprotein genotype and conserved pathway for exceptional longevity in humans.

PLoS biology - 1 Apr 2006

Atzmon Gil, Rincon Marielisa, Schechter Clyde B, Shuldiner Alan R, Lipton Richard B, Bergman Aviv, Barzilai Nir

Abstract excerpt

Alteration of single genes involved in nutrient and lipoprotein metabolism increases longevity in several animal models. Because exceptional longevity in humans is familial, it is likely that polymorphisms in genes favorably influence certain phenotypes and increase the likelihood of exceptional longevity. A group of Ashkenazi Jewish centenarians (n = 213), their offspring (n = 216), and an age-matched Ashkenazi...

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Source

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Identifiers

PMID: 16602826
DOI: 10.1371/journal.pbio.0040113
PMCID: PMC1413567

Genes

APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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