Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae.

Molecules (Basel, Switzerland) - 8 Sept 2017

Chen Huan, Zhang Rong, Luo Rong-Hua, Yang Liu-Meng, Wang Rui-Rui, Hao Xiao-Jiang, Zheng Yong-Tang

Abstract excerpt

APOBEC3G is a member of the human cytidine deaminase family that restricts Vif-deficient viruses by being packaged with progeny virions and inducing the G to A mutation during the synthesis of HIV-1 viral DNA when the progeny virus infects new cells. HIV-1 Vif protein resists the activity of A3G by mediating A3G degradation. Phorbol esters are plant-derived organic compounds belonging to the tigliane family of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC-3G Deaminase
Share to HIV-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phorbol Esters

Share to Plant Extracts

Share to Primary Cell Culture

Share to Protein Kinase C

Share to vif Gene Products, Human Immunodeficiency Virus

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 28885587
DOI: 10.3390/molecules22091498
PMCID: PMC6151696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae.PMID 28885587Read ↗

Bioactive activities of natural products against herpesvirus infectionSemantic proximity Read ↗

Virtual Screening of Kaempferia galanga L. Bioactive Compounds as HPV-16 Antiviral Mechanism Through E6 Inhibitor ActivitySemantic proximity Read ↗

An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.Semantic proximity Read ↗

Reactivation of latent HIV-1 by new semi-synthetic ingenol estersSemantic proximity Read ↗

Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signalingSemantic proximity Read ↗

Differential in vitro Anti-HIV Activity of Natural LignansSemantic proximity Read ↗

Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat.Semantic proximity Read ↗

Activation of Latent HIV-1 Expression by Protein Kinase C Agonists. A Novel Therapeutic Approach to Eradicate HIV-1 ReservoirsSemantic proximity Read ↗

Globoidnan A: a lignan from inhibits HIV integraseSemantic proximity Read ↗

Inhibition by Cellular Vacuolar ATPase Impairs Human Papillomavirus Uncoating and InfectionSemantic proximity Read ↗

Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.Semantic proximity Read ↗

Aurintricarboxylic Acid Inhibits the Early Stage of Vaccinia Virus Replication byTargeting both Cellular and Viral FactorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.