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Article

The role of chemotherapy in microsatellite unstable (MSI-H) colorectal cancer.

International journal of colorectal disease - 1 Jul 2007

Warusavitarne Janindra, Schnitzler Margaret

Abstract excerpt

INTRODUCTION: High-frequency microsatellite instability (MSI-H) is an alternate pathway of colorectal carcinogenesis, which accounts for 15% of all sporadic colorectal cancers. These tumours arise from mutations in the DNA mismatch repair system and thus have different responses to chemotherapeutic agents compared to microsatellite stable (MSS) cancers. OBJECTIVE: This review aims to summarise the available...

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Identifiers

PMID: 17109103
DOI: 10.1007/s00384-006-0228-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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