Article
Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C.
Journal of hepatology - 1 Apr 2007
El-Karef Amro, Kaito Masahiko, Tanaka Hideaki, Ikeda Kazuo, Nishioka Tomohiro, Fujita Naoki, Inada Hiroyasu, Adachi Yukihiko, Kawada Norifumi, Nakajima Yuji, Imanaka-Yoshida Kyoko, Yoshida Toshimichi
Abstract excerpt
BACKGROUND/AIMS: Earlier studies have suggested involvement of tenascin-C (TN-C) in liver fibrosis. Here, we examined expression of TN-C variants and types of alternatively spliced fibronectin-type III (FNIII) repeats in chronic hepatitis. METHODS: Using three monoclonal antibodies against TN-C variants, immunohistochemical staining was performed and the correlation with histological parameters of chronic...
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