Article
The clinical significance of tenascin-C splice variant expression in chondrosarcoma.
Oncology - 1 Jan 2001
Ghert M A, Jung S T, Qi W, Harrelson J M, Erickson H P, Block J A, Scully S P
Abstract excerpt
OBJECTIVES: Tenascin-C (TNC) is an oligomeric glycoprotein of the extracellular matrix that is prominently expressed in malignant tumors. The purpose of this study was: (1) to determine the in vitro TNC splicing pattern in cultured human chondrocytes and chondrosarcoma cells, (2) to determine the in vivo TNC splicing pattern in clinical chondrosarcoma specimens, and (3) to perform survival analysis based on the...
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