Article
HLA and genomewide allele sharing in dizygotic twins.
American journal of human genetics - 1 Dec 2006
Montgomery Grant W, Zhu Gu, Hottenga Jouke Jan, Duffy David L, Heath Andrew C, Boomsma Dorret I, Martin Nicholas G, Visscher Peter M
Abstract excerpt
Gametic selection during fertilization or the effects of specific genotypes on the viability of embryos may cause a skewed transmission of chromosomes to surviving offspring. A recent analysis of transmission distortion in humans reported significant excess sharing among full siblings. Dizygotic (DZ) twin pairs are a special case of the simultaneous survival of two genotypes, and there have been reports of DZ...
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