Article
Quorum-sensing-deficient (lasR) mutants emerge at high frequency from a Pseudomonas aeruginosa mutS strain.
Microbiology (Reading, England) - 1 Jan 2007
Luján Adela M, Moyano Alejandro J, Segura Ignacio, Argaraña Carlos E, Smania Andrea M
Abstract excerpt
In Pseudomonas aeruginosa, quorum sensing constitutes a highly complex cell-to-cell communication system that, along with the cognate acylhomoserine lactone signals and regulators LasR and RhlR, modulates the production of virulence factors and a wide range of metabolic functions. In a previous paper, the authors reported that mismatch repair disruption in P. aeruginosa results in the spontaneous and reproducible...
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