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Article

Simple sequence repeats together with mismatch repair deficiency can bias mutagenic pathways in Pseudomonas aeruginosa during chronic lung infection.

PloS one - 1 Jan 2013

Moyano Alejandro J, Feliziani Sofía, Di Rienzo Julio A, Smania Andrea M

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of mononucleotide G:C and A:T simple sequence repeats (SSRs) in this adaptive process. An in silico survey of the genome sequences of 7 P. aeruginosa strains showed that mononucleotide G:C SSRs but not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Repetitive Sequences, Nucleic Acid

Source

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Identifiers

PMID: 24278287
DOI: 10.1371/journal.pone.0080514
PMCID: PMC3837008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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